Regulatory responses of the adaptive response to alkylation damage: a simple regulon with complex regulatory features.
نویسندگان
چکیده
منابع مشابه
Tiling array study of MNNG treated Escherichia coli reveals a widespread transcriptional response.
The alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) is known to trigger the adaptive response by inducing the ada-regulon - consisting of three DNA repair enzymes Ada, AlkB, AlkA and the enigmatic AidB. We have applied custom designed tiling arrays to study transcriptional changes in Escherichia coli following a MNNG challenge. Along with the expected upregulation of the adaptive r...
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 182 23 شماره
صفحات -
تاریخ انتشار 2000